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Bezanilla, Francisco

One or more keywords matched the following items that are connected to Bezanilla, Francisco

Item Type	Name
Concept	Ion Channels
Concept	Ion Channel Gating
Academic Article	Tracking voltage-dependent conformational changes in skeletal muscle sodium channel during activation.
Academic Article	A physical model of potassium channel activation: from energy landscape to gating kinetics.
Academic Article	Structural biology. Force and voltage sensors in one structure.
Academic Article	Voltage sensor movements.
Academic Article	Coupling interactions between voltage sensors of the sodium channel as revealed by site-specific measurements.
Academic Article	A fluorophore attached to nicotinic acetylcholine receptor beta M2 detects productive binding of agonist to the alpha delta site.
Academic Article	A fluorometric approach to local electric field measurements in a voltage-gated ion channel.
Academic Article	The voltage-sensor structure in a voltage-gated channel.
Academic Article	beta-Scorpion toxin modifies gating transitions in all four voltage sensors of the sodium channel.
Academic Article	Voltage-gated ion channels.
Academic Article	Small vertical movement of a K+ channel voltage sensor measured with luminescence energy transfer.
Academic Article	Gating charge displacement in voltage-gated ion channels involves limited transmembrane movement.
Academic Article	A proton pore in a potassium channel voltage sensor reveals a focused electric field.
Academic Article	Optical detection of rate-determining ion-modulated conformational changes of the ether-à-go-go K+ channel voltage sensor.
Academic Article	Movement of 'gating charge' is coupled to ligand binding in a G-protein-coupled receptor.
Academic Article	A common pathway for charge transport through voltage-sensing domains.
Academic Article	S4-based voltage sensors have three major conformations.
Academic Article	Gating of the bacterial sodium channel, NaChBac: voltage-dependent charge movement and gating currents.
Academic Article	The origin of subconductance levels in voltage-gated K+ channels.
Academic Article	Silicon chip-based patch-clamp electrodes integrated with PDMS microfluidics.
Academic Article	A single charged voltage sensor is capable of gating the Shaker K+ channel.
Academic Article	Coupling between the voltage-sensing and phosphatase domains of Ci-VSP.
Academic Article	Analysis of the optimal channel density of the squid giant axon using a reparameterized Hodgkin-Huxley model.
Academic Article	Controlling the activity of a phosphatase and tensin homolog (PTEN) by membrane potential.
Academic Article	How membrane proteins sense voltage.
Academic Article	Gating currents from Kv7 channels carrying neuronal hyperexcitability mutations in the voltage-sensing domain.
Academic Article	An emerging consensus on voltage-dependent gating from computational modeling and molecular dynamics simulations.
Academic Article	The contribution of individual subunits to the coupling of the voltage sensor to pore opening in Shaker K channels: effect of ILT mutations in heterotetramers.
Academic Article	In search of a consensus model of the resting state of a voltage-sensing domain.
Academic Article	Distance measurements reveal a common topology of prokaryotic voltage-gated ion channels in the lipid bilayer.
Academic Article	Alpha-scorpion toxin impairs a conformational change that leads to fast inactivation of muscle sodium channels.
Academic Article	Ion channels: from conductance to structure.
Academic Article	Molecular mechanism for depolarization-induced modulation of Kv channel closure.
Academic Article	Intermediate state trapping of a voltage sensor.
Academic Article	The voltage sensor and the gate in ion channels.
Academic Article	Detection of the opening of the bundle crossing in KcsA with fluorescence lifetime spectroscopy reveals the existence of two gates for ion conduction.
Academic Article	Properties of deactivation gating currents in Shaker channels.
Academic Article	Control of a final gating charge transition by a hydrophobic residue in the S2 segment of a K+ channel voltage sensor.
Academic Article	IKs channels open slowly because KCNE1 accessory subunits slow the movement of S4 voltage sensors in KCNQ1 pore-forming subunits.
Academic Article	Domain IV voltage-sensor movement is both sufficient and rate limiting for fast inactivation in sodium channels.
Academic Article	Molecular bases for the asynchronous activation of sodium and potassium channels required for nerve impulse generation.
Academic Article	Sensing charges of the Ciona intestinalis voltage-sensing phosphatase.
Academic Article	The gating charge should not be estimated by fitting a two-state model to a Q-V curve.
Academic Article	S3-S4 linker length modulates the relaxed state of a voltage-gated potassium channel.
Academic Article	Moving gating charges through the gating pore in a Kv channel voltage sensor.
Academic Article	Functional Site-Directed Fluorometry.
Academic Article	Resting state of the human proton channel dimer in a lipid bilayer.
Academic Article	Single-molecule fluorimetry and gating currents inspire an improved optical voltage indicator.
Academic Article	Mechanism of functional interaction between potassium channel Kv1.3 and sodium channel NavBeta1 subunit.
Academic Article	Replacing voltage sensor arginines with citrulline provides mechanistic insight into charge versus shape.
Academic Article	Biophysical Characterization of Genetically Encoded Voltage Sensor ASAP1: Dynamic Range Improvement.
Academic Article	Demonstration of ion channel synthesis by isolated squid giant axon provides functional evidence for localized axonal membrane protein translation.
Academic Article	LRET Determination of Molecular Distances during pH Gating of the Mammalian Inward Rectifier Kir1.1b.
Academic Article	Gating currents.
Academic Article	Nonsensing residues in S3-S4 linker's C terminus affect the voltage sensor set point in K+ channels.
Academic Article	Continuum Gating Current Models Computed with Consistent Interactions.
Academic Article	Noncanonical mechanism of voltage sensor coupling to pore revealed by tandem dimers of Shaker.
Academic Article	Metal Bridge in S4 Segment Supports Helix Transition in Shaker Channel.
Academic Article	Gating current noise produced by Brownian models of a voltage sensor.
Academic Article	Tracking the movement of discrete gating charges in a voltage-gated potassium channel.
Academic Article	Ion channel thermodynamics studied with temperature jumps measured at the cell membrane.
Grant	ISS ChronosBH Fluorescence Lifetime Spectrometer
Grant	Surface Plasmon-coupled Fluorescence Microscope to Study Ion Channel Dynamics
Grant	ELECTROPHYSIOLOGICAL STUDIES OF VOLTAGE GATED CHANNELS

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Ion Channel